A Binghamton University assistant professor is investigating technology for the treatment of cancer and autoimmune disorders through the delivery of drugs through antibodies.

Photo: Bob Joseph/WNBF News
Photo: Bob Joseph/WNBF News

Binghamton University says L. Nathan Tumey, assistant professor of pharmaceutical sciences is the leading investigator on two National Institute of Health Grants totaling over $1.3 million to research antibody-mediated drug delivery technology.

So far, Tumey and his collaborators have found a way to attach drugs to a certain area of an antibody: the Glutamine 295 residue, without having to engineer the antibody or make changes to its “backbone.”

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According to a news release from the University, Tumey is the sole investigator on a two-year, $150,000 grant, charmingly entitled “Molecular whack-a-mole” Targeting Transmembrane-TNF alpha for the Delivery of Anti-Inflammatory Drugs.

Professor Tumey says the project is about developing antibody-drug-conjugates that deliver immunosuppressive drugs using antibodies against a particular protein that is only found in inflamed cells hoping to calm that inflammation down.

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